Leptin has become a hot area for obesity research since the discovery of a mutation in the mouse leptin gene that increases the animals’ appetite while lowering their metabolic rate.
Since the discovery of leptin in 1994, many have hoped that the hormone would be a promising weight-loss treatment for humans. Leptin acts as a signal to help the body decide when it has eaten enough food to feel full. The amount of leptin in the blood has been directly linked to body fat.
More fat in the diet decreases leptin levels while a diet higher in carbohydrates increases leptin levels according to a study. Leptin, made by the body’s fat cells, is thought to help contribute to satiety, a feeling of fullness.
When dieting and your leptin levels go down, you may find you are more hungry. Researchers found that during the first week of the weight-loss diet, volunteers’ leptin levels dropped by an average of 54 percent. This is accouding to Agricultural Research Service (ARS) researchers in Davis, California, who are studying the effects of the […]